Prednisolone Bio-Transformation in the Culture of Filamentous Fungus Acremonium strictum
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چکیده
منابع مشابه
Acremostrictin, a highly oxygenated metabolite from the marine fungus Acremonium strictum.
The novel natural product acremostrictin was isolated from the culture broth of Acremonium strictum, a marine fungus collected from a Choristida sponge off the coast of Korea. Structurally, acremostrictin is a tricyclic lactone of an unprecedented skeletal class based on combined spectroscopic and X-ray crystallographic analyses. The new compound exhibited weak antibacterial and moderate antiox...
متن کاملMicrobial hydroxylation of progesterone with Acremonium strictum.
Microbial hydroxylation of progesterone occurred in the culture of Acremonium strictum PTCC 5282 to produce two hydroxylated pregnene-like steroids. The metabolites were purified and characterized using spectroscopic methods and identified as 15alpha-hydroxyprogesterone and 15alpha-hydroxydeoxycorticosterone.
متن کاملResponse of Cellulase Activity in pH-Controlled Cultures of the Filamentous Fungus Acremonium cellulolyticus
Cellulase production was investigated in pH-controlled cultures of Acremonium cellulolyticus. The response to culture pH was investigated for three cellulolytic enzymes, carbomethyl cellulase (CMCase), avicelase, and beta-glucosidase. Avicelase and beta-glucosidase showed similar profiles, with maximum activity in cultures at pH 5.5-6. The CMCase activity was highest in a pH 4 culture. At an ac...
متن کاملCrystal structure of glucooligosaccharide oxidase from Acremonium strictum
Introduction Sugar oxidases and dehydrogenases that catalyze carbohydrate oxidation into the corresponding lactones are of considerable commercial importance. Glucooligosaccharide oxidase (GOOX) from Acremonium strictum was screened with the aim of identifying enzymes with potential applications such as an oligosaccharide acid production and various alternative carbohydrate assays. Screening of...
متن کاملStructural characterization of glucooligosaccharide oxidase from Acremonium strictum.
Glucooligosaccharide oxidase from Acremonium strictum was screened for potential applications in oligosaccharide acid production and carbohydrate detection. This protein is a unique covalent flavoenzyme which catalyzes the oxidation of a variety of carbohydrates with high selectivity for cello- and maltooligosaccharides. Kinetic measurements suggested that this enzyme possesses an open carbohyd...
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ژورنال
عنوان ژورنال: Biotechnology(Faisalabad)
سال: 2008
ISSN: 1682-296X
DOI: 10.3923/biotech.2008.343.346